Taking multiple medications is a common practice. In fact, over half of Americans take at least two, according to the Mayo Clinic. This happens because different medications can manage various aspects of a health condition. Furthermore, individuals, especially older adults, may have multiple health conditions, requiring the combination of additional medications.
Being aware of the risks associated with taking multiple medications is crucial. These risks include a higher chance of side effects and drug interactions, challenges in maintaining medication schedules, and over-prescribing, particularly when multiple healthcare providers are involved without coordinated care.
Certain medication combinations are quite prevalent. GoodRx indicates that the second most common drug combination is lisinopril and metformin. These two are often prescribed together due to their complementary effects beneficial in managing diabetes and heart disease.
Why lisinopril and metformin are often prescribed together
Lisinopril addresses high blood pressure by blocking a substance that constricts blood vessels, allowing them to relax and thereby reducing blood pressure (read this to know how long it takes lisinopril to start working). Lower blood pressure enables more oxygenated blood to reach the heart.
Conversely, metformin aids in controlling blood sugar by decreasing the amount absorbed from food and the sugar produced by the liver. It also enhances the body’s sensitivity to insulin, a hormone regulating blood sugar levels. (Here’s how long it takes metformin to start working.)
Lisinopril and metformin are a common combination because the high blood sugar associated with diabetes damages blood vessels and the heart, increasing the risk of heart disease. By taking both medications, many individuals with type 2 diabetes can better manage their blood sugar and protect their heart health.
Potential drawbacks to combining lisinopril and metformin
While lisinopril and metformin are often prescribed together, they are not entirely free from potential interactions. There is a moderate risk that lisinopril can enhance the blood sugar-lowering effects of metformin, which could cause your blood sugar to drop too low. Signs of low blood sugar include feeling lightheaded, shaky, or unusually tired, along with headaches, intense hunger, irritability, sweating, difficulty concentrating, or a sense of nervousness or confusion.
If you experience low blood sugar while taking these medications, it is important to consult your physician. You may need to monitor your blood sugar more closely, or your doctor might adjust your dosage. Ensuring that all your healthcare providers are informed about all the medications, herbs, and supplements you are taking is equally essential.
